National Red Nose Day is Thursday, May 24, 2018 (5/24/2018) in the USA. What is Red Nose Day? It's a campaign dedicated to actually ending child poverty, run by Comic Relief and featured on an NBC special. Walgreens is the exclusive retailer of red noses. Dozens of celebrities participate, including Jack Black, Jennifer Garner, Kelly Clarkson, Julia Roberts and Ed Sheeran.