Metal-catalyzed addition of saturated carbon into C-C bonds: A relevant reaction for the synthesis type II polyketides
phys.org -

(Phys.org)—Type II polyketides are a class of compounds found in nature as secondary metabolites derived from microorganisms. Their complex structures are characterized by fused polycyclic aromatic rings decorated with a profusion of ketones and hydroxyl groups. Many common antibiotics, anti-fungal, and anti-cancer drugs are type II polyketides or are derivatives of these naturally-occurring compounds. However the "laboratory synthesis" of type II polyketides is often challenging; as in living...

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